Introduction

The aim of the Neurobiology Group is to study the effects of environmental hazards on brain disorders. Brain disorders encompass neurological (i.e.: Alzheimer's disease, sleep disorders, chronic pain, epilepsy, glioblastoma) and neuropsychiatric (i.e.: Depression, anxiety, affective disorders) conditions and diseases. Most of them are multifactorial with interplay between environmental and genetic factors.

The goal of our group is to investigate the effects of environmental hazards on the epigenetics and cellular mechanisms underlying brain disorders and diseases using various methods such as cell culture, biochemistry and immunofluorescence, epigenetic editing with CRISPR-dCas9, epigenomics and proteomics, in vitro electrophysiology, and rodent animal models and behaviors.

Our current projects focus on neurodegenerative diseases and glioblastoma, and we are investigating:

  • The effect mycotoxins on neuronal cells
  • The effect of nanoplastics on pericyte functions and the blood-brain barrier
  • Environmental factors impact on mithochondrial functions of non-neuronal brain cells and the blood-brain barrier
  • Environmental factors impact on the development of glioblastoma

Areas for potential collaboration

We are continuously seeking potential collaborations with all research establishments (universities, institutes and government organisations) to study the effects of environmental agents on brain functions, epigenetics, and behaviour.

Contact us

Contact us if you would like to find out more detail or stay informed about a particular field of research. We are always interested in collaborating and are open to partnerships, to drive forward innovation for the benefit of the public.

 

Contact us